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Showing posts with the label Chemogenetics

Study cautions about the use of designer receptors to control the brain

Chemogenetics is a technique that uses chemicals to understand how neurons are activated. It manipulates genes to place the neurons under the control of special receptors called  DREADDS . Short for Designer Receptors Activated by Designer Drugs, these receptors only bind to an inert chemical called Clozapine-N-Oxide (CNO). In a recent  study , researchers from the Tata Institute of Fundamental Research (TIFR), Mumbai, and Jawaharlal Nehru Center for Advanced Scientific Research (JNCASR), Bengaluru, point out specific flaws in this technique. The study was published in the journal  eNeuro  and funded by the Department of Science and Technology and Scientific and Engineering Research Board. To read the full study, please visit: https://researchmatters.in/news/study-cautions-about-use-designer-receptors-control-brain